Prospects of biomolecule sequencing with the techniques of translocation through nanopores: A review
Identifieur interne : 002115 ( Main/Exploration ); précédent : 002114; suivant : 002116Prospects of biomolecule sequencing with the techniques of translocation through nanopores: A review
Auteurs : V. L. Nosik [Russie] ; E. B. Rudakova [Russie]Source :
- Crystallography Reports [ 1063-7745 ] ; 2013-11-01.
Abstract
Abstract: The interest in the functional properties of biomolecules in native solutions (in particular, their interaction with membranes) constantly increases with accumulation of data on the macromolecular structure, obtained by X-ray diffraction (with synchrotron radiation sources), nuclear magnetic resonance, and mass spectrometry; this interest is closely related to the development of new technologies of sequencing (i.e., determining the sequence of nucleotides in DNA biomolecule). One of the most promising “physical” approaches to sequencing is the application of methods based on the use of nanochannels or nanopores, through which biomolecules pass in ionic solutions under an electric field applied. A nanopore provides spatial localization of molecules and makes it possible to detect a signal (electric, fluorescent, etc.) from an individual nucleotide. In view of the development of new high-intensity pulsed X-ray sources, the popularity of fluorescence analysis constantly increases. The existing methods for simulating the motion of biomolecules and interpreting their structure, sequencing techniques, and the prospects of further development of investigations in this field are discussed.
Url:
DOI: 10.1134/S1063774513060187
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 002282
- to stream Istex, to step Curation: 002282
- to stream Istex, to step Checkpoint: 000253
- to stream Main, to step Merge: 002139
- to stream Main, to step Curation: 002115
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Prospects of biomolecule sequencing with the techniques of translocation through nanopores: A review</title><author><name sortKey="Nosik, V L" sort="Nosik, V L" uniqKey="Nosik V" first="V. L." last="Nosik">V. L. Nosik</name></author><author><name sortKey="Rudakova, E B" sort="Rudakova, E B" uniqKey="Rudakova E" first="E. B." last="Rudakova">E. B. Rudakova</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:DA6C79CFD3A3A2A5B90B5998BBA13ABD4BA377B9</idno><date when="2013" year="2013">2013</date><idno type="doi">10.1134/S1063774513060187</idno><idno type="url">https://api.istex.fr/ark:/67375/VQC-K20T4KQH-F/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">002282</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">002282</idno><idno type="wicri:Area/Istex/Curation">002282</idno><idno type="wicri:Area/Istex/Checkpoint">000253</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000253</idno><idno type="wicri:doubleKey">1063-7745:2013:Nosik V:prospects:of:biomolecule</idno><idno type="wicri:Area/Main/Merge">002139</idno><idno type="wicri:Area/Main/Curation">002115</idno><idno type="wicri:Area/Main/Exploration">002115</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Prospects of biomolecule sequencing with the techniques of translocation through nanopores: A review</title><author><name sortKey="Nosik, V L" sort="Nosik, V L" uniqKey="Nosik V" first="V. L." last="Nosik">V. L. Nosik</name><affiliation wicri:level="3"><country xml:lang="fr">Russie</country><wicri:regionArea>Shubnikov Institute of Crystallography, Russian Academy of Sciences, Leninskii pr. 59, 119333, Moscow</wicri:regionArea><placeName><settlement type="city">Moscou</settlement><region>District fédéral central</region></placeName></affiliation><affiliation wicri:level="1"><country wicri:rule="url">Russie</country></affiliation></author><author><name sortKey="Rudakova, E B" sort="Rudakova, E B" uniqKey="Rudakova E" first="E. B." last="Rudakova">E. B. Rudakova</name><affiliation wicri:level="3"><country xml:lang="fr">Russie</country><wicri:regionArea>Shubnikov Institute of Crystallography, Russian Academy of Sciences, Leninskii pr. 59, 119333, Moscow</wicri:regionArea><placeName><settlement type="city">Moscou</settlement><region>District fédéral central</region></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">Crystallography Reports</title><title level="j" type="abbrev">Crystallogr. Rep.</title><idno type="ISSN">1063-7745</idno><idno type="eISSN">1562-689X</idno><imprint><publisher>Springer US; http://www.springer-ny.com</publisher><pubPlace>Boston</pubPlace><date type="published" when="2013-11-01">2013-11-01</date><biblScope unit="volume">58</biblScope><biblScope unit="issue">6</biblScope><biblScope unit="page" from="805">805</biblScope><biblScope unit="page" to="821">821</biblScope></imprint><idno type="ISSN">1063-7745</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1063-7745</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: The interest in the functional properties of biomolecules in native solutions (in particular, their interaction with membranes) constantly increases with accumulation of data on the macromolecular structure, obtained by X-ray diffraction (with synchrotron radiation sources), nuclear magnetic resonance, and mass spectrometry; this interest is closely related to the development of new technologies of sequencing (i.e., determining the sequence of nucleotides in DNA biomolecule). One of the most promising “physical” approaches to sequencing is the application of methods based on the use of nanochannels or nanopores, through which biomolecules pass in ionic solutions under an electric field applied. A nanopore provides spatial localization of molecules and makes it possible to detect a signal (electric, fluorescent, etc.) from an individual nucleotide. In view of the development of new high-intensity pulsed X-ray sources, the popularity of fluorescence analysis constantly increases. The existing methods for simulating the motion of biomolecules and interpreting their structure, sequencing techniques, and the prospects of further development of investigations in this field are discussed.</div></front></TEI><affiliations><list><country><li>Russie</li></country><region><li>District fédéral central</li></region><settlement><li>Moscou</li></settlement></list><tree><country name="Russie"><region name="District fédéral central"><name sortKey="Nosik, V L" sort="Nosik, V L" uniqKey="Nosik V" first="V. L." last="Nosik">V. L. Nosik</name></region><name sortKey="Nosik, V L" sort="Nosik, V L" uniqKey="Nosik V" first="V. L." last="Nosik">V. L. Nosik</name><name sortKey="Rudakova, E B" sort="Rudakova, E B" uniqKey="Rudakova E" first="E. B." last="Rudakova">E. B. Rudakova</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002115 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002115 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= MersV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:DA6C79CFD3A3A2A5B90B5998BBA13ABD4BA377B9
|texte= Prospects of biomolecule sequencing with the techniques of translocation through nanopores: A review
}}
| This area was generated with Dilib version V0.6.33. |  |